NEW PAPER PUBLISHED BY THE RESEARCH AND DEVELOPMENT DEPARTMENT OF BIOHELLENIKA
R&D Department recenlty published a new paper in Histology-Embryology Journal 2015, issue 30, about the pluripotency of Whartons Jelly stem cells. The umbilical cord Whartons Jelly clasically contains mesenchymal stem cells that are used to treat malignant diseases in combination with cord blood, autoimmune and degenerative diseases. For the last two cases only autologous stem cells can be used.
According to our study, Whartons Jelly contains more than one stem cells populations with different properties. To collect appropriatelly all these populations special techniques must be applied. It is important to use a method that provides the greatest number of stem cells and the collection of all kinds of cord tissue stem cells. Whartons Jelly is a specific embryonic tissue, the only embryonic tissue that remains in newborn, extended out of the external wall of the vessels and clasically contains mesencymal cells. There were some evidence that whartons jelly contains more than one cell population with different properties in cultures.
Biohellenikas R&D group by changing the collection methode discovers a new cell population, more undifferentiated, that matches to embryonic like stem cells (ELSCs), today believed that these are the real stem cells.
These cells also exist in cord blood and needs special collection method, because are smaller than the more mature cells (hematopoietic and mesenchymal), and need one more step for their collection.
ELSCs exist in niche in all organs of the body and provide the regeneration and finally the therapeutic potential into the injured organs. ELSCs in niche are activated by the administered stem cells, migrate into the place of injury and multiple the therapieutic effect.
Taking in mind the importance of these cells in Regenerative Medicine, Biohellenika gives great attention to this cell population, and apply special methods, in routin for its clients, for their collection. First proceed the total length of the cord, second enzymatically digest the cord and the most important third step that collects this small in size population on top of the clasic mesenchymal cells.
This procedure ensures ready to use cells, in great number and best quality for therapeutic application.
Pluripotent stem cells isolated from umbilical cord form embryonic like bodies in a mesenchyma llayer culture. Histology-Embryology 2015 issue 30.
N. Tsagias, Kouzi-Koliakos K, Karagiannis V, Tsikouras P, Koliakos GG.